Expression of Caspase3, P53 and Ki-67 in colon cancer and colon adenoma
نویسندگان
چکیده
منابع مشابه
Expression of Ki-67, p53 and VEGF in pediatric neuroblastoma.
BACKGROUND Neuroblastoma (NB), is a neuroectodermal tumor derived from neural crest cells, and it is the second most common pediatric malignant tumor. The biological and clinical behavior of NB is very heterogeneous. This study was conducted to evaluate the expression of Ki-67, p53 and VEGF markers in tissues obtained from NB patients with different histologic types and stage. MATERIALS AND M...
متن کاملKi-67 and p53 expression in ileal pouches.
Development of dysplastic lesions that may potentially lead to cancer is sometimes reported within the ileal pouches. Dysplasia is in turn associated with increased expression of proliferation indices. The goal of this study was to evaluate the mitotic activity and possible expression of p53 in the epithelium within the ileal pouches in patients with chronic ulcerative colitis. The study invol...
متن کاملChanges in immunoexpression of p53, Ki-67, Ets-1, APAF-1 and PTEN in serrated and conventional colon adenomas.
UNLABELLED The balance between apoptosis and proliferation is tipped towards a decrease of apoptosis as the colonocyte progresses in the adenoma to carcinoma sequence of colon carcinogenesis. According to literature data, proteins like p53, Ki-67, APAF-1, Ets-1, PTEN contribute to inhibition of apoptosis and stimulation of proliferation. AIM Considering the complex interference among colorect...
متن کاملAn immunohistochemical study of P53 and Ki-67 in gastrointestinal adenoma and adenocarcinoma using tissue microarray.
BACKGROUND Gastrointestinal carcinogenesis generally follows the adenoma-adenocarcinoma sequence and tumor metastasis determines the survival time of the patients. The expressions of p53 and ki-67 in gastrointestinal adenoma and adenocarcinoma (GIA) were explored and their clinicopathological significance determined. MATERIALS AND METHODS The expressions of mutant p53 and ki-67 were examined ...
متن کاملevaluation of ki-67 antigen and protein p53 expression in orthokratinized and parakratinized odontogenic keratocyst
statement of problem: odontogenic keratocysts (okc) make up 10-12% of all developmental cysts with dental origin. okcs are classified into parakeratotic and orthokeratotic types, with completely different clinical features. in order to investigate biological behavior of okcs, an immunohistochemical study was designed, using ki-67 antigen as proliferation marker and p53 protein as tumor suppress...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2015
ISSN: 2219-2859
DOI: 10.11569/wcjd.v23.i3.510